Prostate Cancer - Hormone Therapy and Chemotherapy for Prostate Cancer
- Active Surveillance
- Cryosurgery Treatment (Ablation) for Prostate Cancer
- Hormone Therapy and Chemotherapy for Prostate Cancer
- Prostate Cancer Prevention
- Prostate Cancer Surgery
- Radiation Therapy for Prostate Cancer
- Risk Factors and Warning Signs of Prostate Cancer
- Screening and Diagnosis for Prostate Cancer
Eligibility for Hormone Therapy and Chemotherapy for Prostate Cancer
Men with prostate cancer that has spread beyond the prostate gland to other organs, who cannot undergo radiation or surgery to remove the prostate, or whose cancer has recurred following surgery or radiation are candidates for hormonal therapy and/or chemotherapy. In some patients these therapies are also given along with radiation or surgery.
Hormone Therapy for Prostate Cancer
Hormone therapy is designed to reduce the levels of the male hormones (androgens) that fuel the growth of prostate cancer cells. Doctors reduce hormone levels by either surgically removing the testicles (an orchiectomy), the source of most androgens, or by using drugs that lower or suppress testosterone levels.
Doctors at Columbia Urology are currently evaluating the use of intermittent hormonal therapy to decrease the side effects of hormone deprivation. Common side effects include hot flashes and sweating, swelling of or tenderness in the breasts, trouble sleeping, and impotence or decrease in sex drive. We are also investigating the use of agents that prevent bone loss and reduce the side effects of hormone therapy.
Chemotherapy for Prostate Cancer
For years, chemotherapy was not a promising treatment approach for men with prostate cancer because of its limited effectiveness and side effects. But a number of new therapies are under study in men with advanced disease, and recent studies by Columbia Urology's Dr. Daniel Petrylak demonstrate that prostate cancer may not be as resistant to chemotherapy as once thought. Results of early clinical studies have shown a combination of chemotherapeutic agents to be very effective and well tolerated in men whose prostate cancer is unresponsive to hormonal medications.
Dr. Petrylak has reported that the use of the chemotherapeutic regimen taxotere/emcyt to treat patients who have failed hormonal therapy achieves an 80% response rate. These medications promise to have a major impact on advanced prostate cancer, particularly in those patients that are unresponsive to commonly used drugs.
Columbia Urology is in the process of enrolling patients in a number of clinical trials of new agents to treat prostate cancer. For more information click here.
Herbert Irving Pavilion & ColumbiaDoctors Midtown
Morgan Stanley Children's Hospital of NewYork-Presbyterian
Dr. Ketan Badani and colleagues' article on the "Evolution of Robotic Radical Prostatectomy, an Assessment After 2766 Procedures," was published in the November 1, 2007 issue of Cancer, a journal of the American Cancer Society.
Prostate Cancer Diagnostic and Evaluation Procedures
Prostate Health Glossary
Chemotherapy For Prostate Cancer
Anatomy of the Prostate Gland
Herbal Remedies: Prostate Cancer
Radiation Therapy for Prostate Cancer
Prostate Cancer Surgery
Prostate Cancer Staging
Prostate Cancer Psychosocial Factors
For Family Members Coping With Prostate Cancer
Prostate Cancer Expectant Therapy
Prostate Cancer Clinical Trials
Prostate Cancer Statistics
Prostate Cancer Symptoms
Prostate Cancer Risk Factors
Prostate Cancer in African-American Men
Prostate Cancer Grading
About Prostate Cancer