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Bladder Trials

Nab Rapamycin 

Name: A Combined Phase 1 and Phase 2 Study of Albumin-bound Rapamycin Nanoparticles in the Treatment of BCG Refractory or Recurrent Nonmuscle Invasive Transitional Cell Bladder Cancer

Description: The purpose of this study is to determine appropriate dosing of Albumin-bound Rapamycin and evaluate its safety and anti-tumor activity in the treatment of non-muscle invasive bladder cancer.

Status: Phase 1 is closed for recruitment. Recruitment for Phase 2 to begin soon.

Contact Info: 212-305-6665; ico2106@cumc.columbia.edu

Link: https://clinicaltrials.gov/ct2/show/NCT02009332

Cysview

Name: A Prospective, Multicenter Phase 3 Study of Blue Light Cystoscopy With Cysview and White Light Cystoscopy Using KARL STORZ D-Light C PDD Flexible Videoscope System in Detection of Bladder Cancer in Patients With Bladder Cancer

Description: The purpose of this study is to investigate if blue light cystoscopy with Cysview improves detection of tumors in patients with bladder cancer during surveillance cystoscopy, using the KARL STORZ D-Light C PDD Flexible Videoscope System. Another purpose is to investigate if Cysview and blue light is safe and effective when used repeatedly.

Status: Recruitment to begin shortly. 

Contact Info: 212-932-4309; gjd16@cumc.columbia.edu

Link: https://clinicaltrials.gov/ct2/show/study/NCT02560584

CGC

Name: Intravesical Cabazitaxel, Gemcitabine, and Cisplatin (CGC) in the Treatment Urothelial Carcinoma of the Bladder

Description: A combined phase I trial to assess the safety, toxicity, and efficacy of a novel multidrug intravesical regimen consisting of Cabazitaxel, Gemcitabine, and Cisplatin (CGC) in the treatment of BCG resistant non-muscle invasive urothelial carcinoma of the bladder. This phase I trial will have a combined dose and cycle-escalation scheme with enrollment of up to 24 patients.

Status: Open for recruitment

Contact info: 212-305-5526; ws2375@columbia.edu

Link: https://clinicaltrials.gov/ct2/show/NCT02202772